Acute/Chronic Toxicity Analysis Services

This service assesses the toxic effects of chemical substances on organisms under acute or chronic exposure conditions using C. elegans as a model organism.

· Acute toxicity: Examines short-term, high-dose exposure effects, typically within 24 hours, focusing on mortality and immediate toxic reactions.

· Chronic toxicity: Investigates long-term, low-dose exposure impacts on growth, reproduction, behavior, and physiological functions, providing insights into cumulative toxicity.

With its short life cycle and ease of handling, C. elegans is an excellent model for studying both immediate and generational toxic effects. Theses evaluations enable comprehensive the toxic effects of target substances, covering growth inhibition, changes in reproductive capacity, neurotoxicity, and organ damage. Whether it is drug toxicity evaluation or environmental monitoring, SunyBiotech can provide you with reliable data support to help you quickly and accurately identify potential toxic risks.

Our services include but are not limited to:

High-Dose Mortality Analysis--The nematodes were exposed to high doses toxins and the number of surviving nematodes was counted.

Fig.1 Changes in the number of Caenorhabditis elegans surviving after exposure to toxicants

Long-Term Low-Dose Toxicity Analysis--Asses the effects of chronic low-dose exposure on growth, development, behavior, fertility, metabolism and other physiological and biochemical aspects.