The avoidance behavior of C. elegans refers to its motor response to environmental stimuli such as chemicals, temperature, oxygen, etc. Depending on the nature of the stimulus, C. elegans exhibites either approach (attraction) or avoidance (repulsion) behavior, which is crucial for locating food, avoiding harm, or maintain physiological balance.
By studying these behaviors, SunyBiotech can help you explore how the nervous system responds external stimuli and how environmental factors or chemical exposures alter behavior. This provides key insights into sensory processing and biological effects of various substances.
Fig.1 Olfactory preference changes depending on the odour concentration in C. elegans. (Yoshida K, et al ., 2012)
Application of Approach-Avoidance Behavior Analysis
uSurvival and Reproduction
Avoidance behavior helps C. elegans in escaping potential dangers such as toxins or unsuitable environments, enhancing survival. Chemotactic responses help locate suitable habitats nutrient sources, and promote reproduction.
uEnvironmental Adaptation
Approach-avoidance behavior enable C. elegans to adapt to environmental changes, making them ideal for evaluating the effects of environmental factors on the overall behavior.
uNervous System Function Research
With simple neural structure and quantifiable approach-avoidance behavior, C. elegans serves as a model for studying neural circuits, learning and memory.
uDrug Discovery and Toxicity Assessment
Avoidance behavior is a biomarker for environmental toxicity, drug response, faciliting the evaluation of compound safety and potential toxicity.
Our Services
ØApproach and Avoidance Behavior Analysis
We analyze C. elegans avoidance responses to various chemical substances(e.g.,: isoamyl alcohol, butanone, sodium chloride, alcohol, etc) under different concentrations. Movement behavior during the avoidance are also assessed to provide a comprehensive view of responses.
Related Services
For analysis of the approach and avoidance behavior of C. elegans to temperature, oxygen, etc., please refer to: C. elegans stress analysis service
References
1. Yoshida K, Hirotsu T, Tagawa T, et al. Odour concentration-dependent olfactory preference change in C. elegans. Nat Commun. 2012;3:739. Published 2012 Mar 13. doi:10.1038/ncomms1750.
