An in vivo genome-wide CRISPR identifies a key regulator of myeloid leukemia

RNA-binding proteins play important roles in maintaining drug resistance of leukemia. In a recent research, team of Dr. Tannishtha Reya from University of California San Diego revealed that the double...

The gene-edited cells are helping: an update of the first patient in the US to get treated for SCD by CRISPR gene editing

Sickle cell disease (SCD) is a group of inherited red blood cell disorders. The disease is caused by a genetic mutation that produces a defective form of hemoglobin, the protein in red blood cells tha...

How Dopamine System Helps coordinate behaviors

To detect on worms for days in a row, Picower Institute scientists think up a open-source microscopy platform.

A novel genomic multiplexed editing metho—CHyMErA

Cas Hybrid for Multiplexed Editing and Screening application (CHyMErA) is a new gene editing technique.

CRISPR as an antiviral strategy to combat SARS-CoV-2 and influenza

PAC-MAN strategy represents a potentially powerful new approach for inhibiting viral function and replication, and they envision it could be useful for a diverse array of circulating and emergent viral threats

The world’s first complete gene editing phase I clinical trial completed in China: safe and effective

Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer

Can Smells Make You Fat?

Olfactory and metabolic dysfunctions are intertwined phenomena associated with obesity and neurodegenerative diseases; yet how mechanistically olfaction regulates metabolic homeostasis remains unclear

Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice

Induction of neurons with dopaminergic features in PD model mice

Potential New CRISPR/Cas System with No Limits!

New study proposes two artificially modified Cas enzymes, SpG and SpRY, in which SpRY can have almost unrestricted editing activity on the entire sequence.

CRISPR Pioneer Doudna Opens Bay Area Lab to Run COVID-19 Tests

Jennifer Doudna has turned a scientific laboratory into a test area for running medical test for COVID-19