C. elegans Cell Invasion Model Helps Study of Cancer Cell Metastasis Mechanism

Cancer has become one of the serious threats to human health, and its treatment has become the focus of global medical strategy. Cancer metastasis is an important reason for its high lethality. Genera...

CRISPR-engineered T cells in patients with refractory cancer

Tumor immunotherapy brings new strategies and hope to tumor treatment. The use of immune cells for anti-tumor treatment has greatly improved the clinical treatment of tumors. Recently, Carl H. June an...

Two Conserved Epigenetic Regulators Prevent Healthy Ageing

Aging is the physiological process in which the physiological functions of the organism gradually degenerate and eventually lead to death, and it is also one of the most serious risk factors for some ...

The Great Function of HPX-2--Nematode Serotonin Peroxidase

Recently, the outbreak of corona virus in Wuhan has arose wide concern around the world.In fact, the more terrifying is fear rather than infec...

The Standards of Making Definite Diagnosis of Wuhan Novel Coronavirus Pneumonia

The novel coronavirus pneumonia outbreaks in Wuhan, China in the end of 2019 presents high infectiousness and has caused thousands of deaths. Performing nucleic acid test of COVID-19 by RT-PCR is one ...

Worm lifespan can be extended by 500 percent

The finding suggest that aging is not simply the result of one specific gene or pathway acting on its own, but rather combinations of genes or pathways interacting with each other, which may explain why no single specific gene that extends longevity in humans has been found.

Reactivation of γ-globin expression through Cas9 or base editor to treat β-hemoglobinopathies

Mutations in the β-globin gene, the essential component of adult hemoglobin (HbA; α2β2), results in either a production of aberrant sickle hemoglobin leading to sickle cell disease or an insufficie...

The CRISPR/Cas9 gene editing system has been widely used in the basic biomedical research. However, the preclinical safety of the CRISPR/Cas9 system lacks a comprehensive assessment. Previous studies have shown that the CRISPR/Cas9 system causes a large n

The CRISPR/Cas9 gene editing system has been widely used in the basic biomedical research. However, the preclinical safety of the CRISPR/Cas9 system lacks a comprehensive assessment. Previous studies ...

The key of curing AIDS and the controversy of genomic edit

In 1996, Hongkui Deng Ph.D of NYU discovered CCR5, which lately becomes one of the keys of curing AIDS. Scientists found that in people with innate mutation of CCR5-∆32, HIV-1 is not able to bind wit...

Multiple sensory neurons modify the gustatory preference in C. elegans

Animals show behavioral plasticity through learning. Integrated multiple sensory inputs play a key role in generating proper behavioral output. In C. elegans, behavioral responses to NaCl is plastic a...